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Safety examinations are saved intensive and include serial hepatic, renal, cardiovascular function tests, haematology profiles and adverse event monitoring with special attention of combined administration of supplements with chemotherapeutics or endocrine agents rated to have organ-specific toxicity risk

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5, 6, 7, 8 Evidence of neuroimmune involvement in the cerebellum includes the presence of activated neuroglia and elevated cytokine levels, as well as autoantibodies to cerebellar proteins

Matsukura T, Tanaka H